Pfizer Inc
Pfizer Inc (PFE) Options Open Interest
PFE options open interest is 2,144,493 contracts. The 2-week average daily volume is 101,663 contracts across the chain.
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Monitoring PFE open interest helps you see where real money is positioned on Pfizer Inc's options and which strikes are attracting the most commitment from traders. Pfizer Inc's open interest reflects the total number of outstanding contracts that have not been closed or exercised, making it a powerful gauge of liquidity, conviction, and potential support and resistance zones. Use our scanner to monitor PFE options open interest in real time and find the strikes that matter.
Open interest is distinct from volume: volume counts how many contracts are traded in a session, while open interest counts how many remain open at the end of the day. Rising PFE options open interest alongside rising volume suggests new positions are being built, while falling open interest signals positions are being closed. Heavy open interest at specific strikes often acts as a magnet near expiration and can hint at where dealers and large traders expect Pfizer Inc to settle.
Pfizer Inc. discovers, develops, manufactures, markets, distributes, and sells biopharmaceutical products worldwide. It offers medicines and vaccines in various therapeutic areas, including cardiovascular metabolic and women's health under the Premarin family and Eliquis brands; biologics, small molecules, immunotherapies, and biosimilars under the Ibrance, Xtandi, Sutent, Inlyta, Retacrit, Lorbrena, and Braftovi brands; and sterile injectable and anti-infective medicines, and oral COVID-19 treatment under the Sulperazon, Medrol, Zavicefta, Zithromax, Vfend, Panzyga, and Paxlovid brands. The company also provides medicines and vaccines in various therapeutic areas, such as pneumococcal disease, meningococcal disease, tick-borne encephalitis, and COVID-19 under the Comirnaty/BNT162b2, Nimenrix, FSME/IMMUN-TicoVac, Trumenba, and the Prevnar family brands; biosimilars for chronic immune and inflammatory diseases under the Xeljanz, Enbrel, Inflectra, Eucrisa/Staquis, and Cibinqo brands; and amyloidosis, hemophilia, and endocrine diseases under the Vyndaqel/Vyndamax, BeneFIX, and Genotropin brands.
In addition, the company is involved in the contract manufacturing business. It serves wholesalers, retailers, hospitals, clinics, government agencies, pharmacies, and individual provider offices, as well as disease control and prevention centers. The company has collaboration agreements with Bristol-Myers Squibb Company; Astellas Pharma US, Inc.; Myovant Sciences Ltd.; Akcea Therapeutics, Inc; Merck KGaA; Valneva SE; BioNTech SE; and Arvinas, Inc. Pfizer Inc. was founded in 1849 and is headquartered in New York, New York.
Pin risk into expiration, dealer positioning, liquidity checks for large orders — all of it starts with knowing where PFE open interest is concentrated. Our scanner maps Pfizer Inc's open interest across every strike and expiry, flags unusual buildups, and lets you drill into the contracts that institutional money is actually holding. Trade Pfizer Inc's options open interest as the signal it is, not as an afterthought.
| 28.50 | 0.43 | 0.48 | 0.46 | 23% | +0.5920 | 16,184 |
| 29.00 | 0.20 | 0.21 | 0.21 | 22% | +0.3630 | 4,014 |
| 28.00 | 0.76 | 0.85 | 0.81 | 23% | +0.7837 | 2,697 |
| 30.00 | 0.02 | 0.04 | 0.03 | 23% | +0.0764 | 2,661 |
| 26.00 | 2.59 | 2.80 | 2.70 | 33% | +0.9876 | 1,847 |
| 27.00 | — | 0.03 | 0.03 | 29% | -0.0603 | 5,050 |
| 27.50 | 0.04 | 0.05 | 0.05 | 25% | -0.0985 | 1,149 |
| 28.00 | 0.10 | 0.13 | 0.12 | 23% | -0.2171 | 1,013 |
| 26.50 | — | 0.03 | 0.03 | 36% | -0.0501 | 668 |
| 26.00 | — | 0.01 | 0.01 | 36% | -0.0194 | 490 |
As of September 25, 2026
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