Septerna Inc
Septerna Inc (SEPN) Wheel Strategy
SEPN wheel strategy scan found 19 cash-secured put setups on the previous trading day. Probability of expiring worthless is above 50%. Annualized returns reach up to 115.2%.
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Running a SEPN wheel strategy lets you generate consistent premium income on Septerna Inc while setting your own entry and exit prices on the underlying. Septerna Inc's wheel combines cash-secured puts and covered calls into a repeatable cycle: sell puts at strikes where you'd be happy to own SEPN, and if assigned, sell calls at strikes where you'd be happy to sell. Use our scanner to find the best SEPN wheel strategy setups in real time.
The wheel works best on liquid, high-quality names with stable fundamentals and active options markets — exactly the profile many large-cap leaders fit. The mechanics are simple: sell a cash-secured put on SEPN, collect premium, and either keep the premium if it expires worthless or take assignment at a discount to current price. Once assigned, sell covered calls against the shares to keep collecting premium until they're called away. Choosing the right strikes, expirations, and IV environment is what separates a profitable SEPN wheel from a losing one.
Septerna, Inc., a clinical-stage biotechnology company, discovers and develops G protein-coupled receptor (GPCR) oral small molecule products candidates for the treatment of endocrinology, immunology and inflammation, and metabolic diseases. The company develops SEP-786, an oral small molecule PTH1R agonist for hypoparathyroidism; SEP-631, an oral small molecule MRGPRX2 NAM for chronic spontaneous urticaria and other mast cell diseases; TSHR Program, an oral small molecule TSHR NAM for Graves' disease and thyroid eye disease. It also develops oral small molecule single- and multi-incretin receptor agonists for metabolic disorders including obesity and type 2 diabetes.
Septerna, Inc. was formerly known as GPCR NewCo, Inc. and changed its name to Septerna Inc. in June 2021. The company was incorporated in 2019 and is headquartered in South San Francisco, California.
The difference between a wheel that compounds and one that bleeds comes down to strike selection, IV timing, and discipline on assignment. Our scanner handles the heavy lifting: it ranks every leg of the SEPN wheel strategy by delta, premium yield, IV rank, and days to expiration, so you can deploy capital where the math works. Build your SEPN wheel strategy on data, not gut feel — and let the options wheel do what it does best: pay you to wait.
| Oct 16, 2026 | 36.00 | $0.10 | $2.50 | -0.36 | 22 | 42% | 59.3% | 115.2% | 0 |
| Oct 16, 2026 | 37.00 | $0.10 | $2.50 | -0.40 | 22 | 42% | 53.4% | 112.1% | 0 |
| Nov 20, 2026 | 35.00 | $1.15 | $3.33 | -0.33 | 57 | 42% | 56.4% | 60.8% | 0 |
| Nov 20, 2026 | 36.00 | $1.00 | $3.25 | -0.36 | 57 | 42% | 52.7% | 57.8% | 0 |
| Nov 20, 2026 | 34.00 | $0.50 | $2.70 | -0.30 | 57 | 42% | 60.2% | 50.9% | 0 |
| Nov 20, 2026 | 32.00 | $0.10 | $2.50 | -0.25 | 57 | 42% | 67.9% | 50.0% | 0 |
| Nov 20, 2026 | 33.00 | $0.25 | $2.58 | -0.27 | 57 | 42% | 64.1% | 50.0% | 0 |
| Jan 15, 2027 | 35.00 | $3.10 | $5.30 | -0.33 | 113 | 42% | 51.0% | 48.9% | 1 |
| Jan 15, 2027 | 34.00 | $2.60 | $4.80 | -0.31 | 113 | 42% | 53.8% | 45.6% | 1 |
| Apr 16, 2027 | 30.00 | $5.80 | $7.15 | -0.23 | 204 | 42% | 57.3% | 42.6% | 1 |
As of September 25, 2026
Run the Wheel on SEPN With Confidence
Find the best SEPN wheel strategy setups across strikes and expirations, plan ahead with at-strike values, and keep your covered calls and puts on track.
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