Puma Biotechnology Inc
Puma Biotechnology Inc (PBYI) Unusual Options Activity Today
PBYI options volume power reached 0.41x on the previous trading day. The highest reading was on the $12.5 CALL expiring 2027-03-19.
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Checking PBYI unusual options activity helps you spot when traders are making outsized bets on Puma Biotechnology Inc before the broader market catches on. Puma Biotechnology Inc's unusual options activity flags contracts trading at multiples of their average daily volume, often signaling that informed money is positioning ahead of a catalyst. Use our scanner to monitor PBYI unusual options activity today and surface the prints that deserve a second look.
Unusual options flow typically refers to trades where volume vastly exceeds open interest at a given strike, or where total contract volume on a name spikes well above its norm. Watching PBYI unusual options flow today can reveal large block trades, sweeps across exchanges, and aggressive directional bets. Tracking PBYI unusual options volume across calls and puts helps you separate hedging activity from genuinely speculative positioning, and PBYI unusual options flow data becomes especially valuable around earnings, product launches, and macro events.
Puma Biotechnology, Inc., a biopharmaceutical company, focuses on the development and commercialization of products to enhance cancer care in the United States and internationally. The company's drug candidates include PB272 neratinib (oral) for the patients with early stage HER2-overexpressed/amplified breast cancer; PB272 (neratinib, oral) for the use of neratinib in combination with capecitabine for the treatment of adult patients with advanced or metastatic HER2-positive breast cancer; PB272 (neratinib, oral) for HER2 mutation-positive solid tumors. It has a license agreement with Pfizer, Inc.; and sub-license agreement with Specialised Therapeutics Asia Pte Ltd., CANbridge BIOMED Limited, Pint Pharma International SA, Knight Therapeutics, Inc., Pierre Fabre Medicament SAS, and Bixink Therapeutics Co., Ltd.
The company was founded in 2010 and is headquartered in Los Angeles, California.
Catalysts rarely arrive without a footprint, and PBYI unusual options activity is often where that footprint shows up first. Our scanner tracks Puma Biotechnology Inc's unusual options flow in real time, ranks prints by volume-to-open-interest, premium spent, and aggressor side, and separates real conviction from noise. Whether you're looking at PBYI unusual options volume on the call side or chasing put sweeps, Puma Biotechnology Inc's unusual options flow today is one click away, so put it on your radar before the headlines hit.
| 10.00 | — | 0.55 | 0.55 | 77% | 1 | 444 | 0.23% |
| 2.50 | 5.00 | 9.50 | 7.25 | 84% | 0 | 0 | — |
| 5.00 | 2.50 | 7.00 | 4.75 | 48% | 0 | 0 | — |
| 7.50 | 0.40 | 4.90 | 2.65 | 159% | 0 | 5 | 0.00% |
| 12.50 | — | 0.50 | 0.50 | 157% | 0 | 11 | 0.00% |
| 2.50 | — | 3.80 | 3.80 | 1,000% | 0 | 0 | — |
| 5.00 | — | 0.05 | 0.05 | 185% | 0 | 0 | — |
| 7.50 | — | 1.00 | 1.00 | 268% | 0 | 42 | 0.00% |
| 10.00 | — | 1.00 | 1.00 | 107% | 0 | 27 | 0.00% |
| 12.50 | 0.70 | 4.90 | 2.80 | 90% | 0 | 0 | — |
As of September 30, 2026
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