Protagonist Therapeutics Inc
Protagonist Therapeutics Inc (PTGX) Options Open Interest
PTGX options open interest is 6,941 contracts. The 2-week average daily volume is 71 contracts across the chain.
Read more
Monitoring PTGX open interest helps you see where real money is positioned on Protagonist Therapeutics Inc's options and which strikes are attracting the most commitment from traders. Protagonist Therapeutics Inc's open interest reflects the total number of outstanding contracts that have not been closed or exercised, making it a powerful gauge of liquidity, conviction, and potential support and resistance zones. Use our scanner to monitor PTGX options open interest in real time and find the strikes that matter.
Open interest is distinct from volume: volume counts how many contracts are traded in a session, while open interest counts how many remain open at the end of the day. Rising PTGX options open interest alongside rising volume suggests new positions are being built, while falling open interest signals positions are being closed. Heavy open interest at specific strikes often acts as a magnet near expiration and can hint at where dealers and large traders expect Protagonist Therapeutics Inc to settle.
Protagonist Therapeutics, Inc., a biopharmaceutical company, discovers and develops peptide-based therapeutic drugs to address hematology and blood disorders, and inflammatory and immunomodulatory diseases. It is developing rusfertide (PTG-300), an injectable hepcidin mimetic that is in Phase II clinical trials for the treatment of patients with polycythemia vera and hereditary hemochromatosis, as well as for the treatment of other blood disorders; PN-943, an oral, alpha-4-beta-7 integrin- specific antagonist peptide that is in Phase II clinical trials for treating inflammatory bowel disease (IBD); and PN-235, an orally delivered interleukin-23 receptor specific antagonist for the treatment of IBD and non-IBD indications.
The company has a license and collaboration agreement with Janssen Biotech, Inc. Protagonist Therapeutics, Inc. was incorporated in 2006 and is headquartered in Newark, California.
Pin risk into expiration, dealer positioning, liquidity checks for large orders — all of it starts with knowing where PTGX open interest is concentrated. Our scanner maps Protagonist Therapeutics Inc's open interest across every strike and expiry, flags unusual buildups, and lets you drill into the contracts that institutional money is actually holding. Trade Protagonist Therapeutics Inc's options open interest as the signal it is, not as an afterthought.
| 150.00 | 2.50 | 4.10 | 3.30 | 53% | +0.3042 | 133 |
| 135.00 | 6.90 | 11.00 | 8.95 | 50% | +0.6181 | 36 |
| 145.00 | 2.70 | 6.50 | 4.60 | 51% | +0.3951 | 36 |
| 165.00 | — | 4.90 | 4.90 | 95% | +0.2728 | 32 |
| 65.00 | 72.20 | 76.50 | 74.35 | 165% | +0.9799 | 31 |
| 95.00 | — | 4.90 | 4.90 | 171% | -0.1342 | 61 |
| 125.00 | — | 4.90 | 4.90 | 80% | -0.2631 | 26 |
| 130.00 | 0.50 | 4.80 | 2.65 | 46% | -0.2599 | 20 |
| 135.00 | 2.50 | 6.30 | 4.40 | 46% | -0.3760 | 11 |
| 160.00 | 19.50 | 24.30 | 21.90 | 47% | -0.8716 | 10 |
As of September 23, 2026
Follow the money
Track PTGX open interest across every strike and expiration, identify where conviction is building, and trade with the positioning data on your side.
Start your 14-day free trial→