Pyxis Oncology Inc

PYXSNASDAQ · USD
3.19USD-0.14 (-4.21%)
1210

Pyxis Oncology Inc (PYXS) Options Open Interest

PYXS options open interest is 7,505 contracts. The 2-week average daily volume is 267 contracts across the chain.

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Monitoring PYXS open interest helps you see where real money is positioned on Pyxis Oncology Inc's options and which strikes are attracting the most commitment from traders. Pyxis Oncology Inc's open interest reflects the total number of outstanding contracts that have not been closed or exercised, making it a powerful gauge of liquidity, conviction, and potential support and resistance zones. Use our scanner to monitor PYXS options open interest in real time and find the strikes that matter.

Open interest is distinct from volume: volume counts how many contracts are traded in a session, while open interest counts how many remain open at the end of the day. Rising PYXS options open interest alongside rising volume suggests new positions are being built, while falling open interest signals positions are being closed. Heavy open interest at specific strikes often acts as a magnet near expiration and can hint at where dealers and large traders expect Pyxis Oncology Inc to settle.

Pyxis Oncology, Inc., a preclinical stage biopharmaceutical company, engages in the development of therapies to treat cancers. Its immune-oncology product candidates include PYX-106, an investigational fully human immunoglobulin G1 isotype siglec-15 targeting antibody for the treatment of thyroid cancer, head and neck squamous cell carcinoma, non-small cell lung cancer (NSCLC), and other solid tumors; and PYX-102, an investigational immune-therapeutic for treatment of solid tumors. The company's antibody drug conjugate (ADC) product candidates comprise of PYX-201, an investigational novel ADC to treat NSCLC, breast cancer, and other solid tumors; PYX-202, an investigational novel ADC for treatment of SCLC, soft tissue sarcoma, and other solid tumors; and PYX-203, an investigational ADC for the treatment of acute myeloid leukemia and myeloid dysplastic syndrome.

The company was incorporated in 2018 and is headquartered in Cambridge, Massachusetts.

Pin risk into expiration, dealer positioning, liquidity checks for large orders — all of it starts with knowing where PYXS open interest is concentrated. Our scanner maps Pyxis Oncology Inc's open interest across every strike and expiry, flags unusual buildups, and lets you drill into the contracts that institutional money is actually holding. Trade Pyxis Oncology Inc's options open interest as the signal it is, not as an afterthought.

2026-10-16
Calls
5.000.100.250.18162%+0.24533,552
2.500.601.200.90103%+0.8798361
1.501.502.502.00311%+0.9144135
7.500.050.200.13223%+0.152149
1.002.003.002.50446%+0.945225
Puts
2.500.100.200.15144%-0.1752192
5.001.202.201.70107%-0.8922127
2.000.050.05148%-0.070754
0.500.050.05486%-0.018115
1.000.050.05310%-0.03222

As of September 18, 2026

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Track PYXS open interest across every strike and expiration, identify where conviction is building, and trade with the positioning data on your side.

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