Karyopharm Therapeutics Inc

KPTINASDAQ · USD
1.22USD0.00 (+1.25%)
142

Karyopharm Therapeutics Inc (KPTI) Unusual Options Activity Today

KPTI options volume power reached 5x on the previous trading day. The highest reading was on the $0.5 PUT expiring 2027-01-15.

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Checking KPTI unusual options activity helps you spot when traders are making outsized bets on Karyopharm Therapeutics Inc before the broader market catches on. Karyopharm Therapeutics Inc's unusual options activity flags contracts trading at multiples of their average daily volume, often signaling that informed money is positioning ahead of a catalyst. Use our scanner to monitor KPTI unusual options activity today and surface the prints that deserve a second look.

Unusual options flow typically refers to trades where volume vastly exceeds open interest at a given strike, or where total contract volume on a name spikes well above its norm. Watching KPTI unusual options flow today can reveal large block trades, sweeps across exchanges, and aggressive directional bets. Tracking KPTI unusual options volume across calls and puts helps you separate hedging activity from genuinely speculative positioning, and KPTI unusual options flow data becomes especially valuable around earnings, product launches, and macro events.

Karyopharm Therapeutics Inc., a commercial-stage pharmaceutical company, discovers, develops, and commercializes drugs directed against nuclear export for the treatment of cancer and other diseases. The company discovers, develops, and commercializes novel and Selective Inhibitor of Nuclear Export (SINE) compounds function by binding with and inhibiting the nuclear export protein XPO1. Its lead compound, include XPOVIO in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myeloma, in combination with dexamethasone for the treatment of adult patients with heavily pretreated multiple myeloma, and for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma.

The company has license agreement with Menarini Group to develop and commercialize NEXPOVIO for human oncology indications in Europe, including the United Kingdom; Latin America; and other countries. Its oral SINE compounds also designed to force nuclear accumulation in the levels of multiple tumor suppressor and growth regulatory proteins. The company was incorporated in 2008 and is headquartered in Newton, Massachusetts.

Catalysts rarely arrive without a footprint, and KPTI unusual options activity is often where that footprint shows up first. Our scanner tracks Karyopharm Therapeutics Inc's unusual options flow in real time, ranks prints by volume-to-open-interest, premium spent, and aggressor side, and separates real conviction from noise. Whether you're looking at KPTI unusual options volume on the call side or chasing put sweeps, Karyopharm Therapeutics Inc's unusual options flow today is one click away, so put it on your radar before the headlines hit.

2026-10-16
Calls
1.00—0.400.40314%16963826.49%
2.00—0.250.25436%11850.54%
1.500.050.200.13216%176,8570.25%
2.500.050.250.15398%112,7870.01%
0.500.550.850.7053%80—
Puts
2.000.550.950.7526%232979.31%
1.000.051.000.53733%5424522.04%
0.50—0.050.05402%0500.00%
1.50—1.001.00836%01650.00%
2.500.701.701.2036%00—

As of September 29, 2026

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