Zentalis Pharmaceuticals Inc
Zentalis Pharmaceuticals Inc (ZNTL) Options Open Interest
ZNTL options open interest is 7,484 contracts. The 2-week average daily volume is 299 contracts across the chain.
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Monitoring ZNTL open interest helps you see where real money is positioned on Zentalis Pharmaceuticals Inc's options and which strikes are attracting the most commitment from traders. Zentalis Pharmaceuticals Inc's open interest reflects the total number of outstanding contracts that have not been closed or exercised, making it a powerful gauge of liquidity, conviction, and potential support and resistance zones. Use our scanner to monitor ZNTL options open interest in real time and find the strikes that matter.
Open interest is distinct from volume: volume counts how many contracts are traded in a session, while open interest counts how many remain open at the end of the day. Rising ZNTL options open interest alongside rising volume suggests new positions are being built, while falling open interest signals positions are being closed. Heavy open interest at specific strikes often acts as a magnet near expiration and can hint at where dealers and large traders expect Zentalis Pharmaceuticals Inc to settle.
Zentalis Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, focuses on discovering and developing small molecule therapeutics for the treatment of various cancers. Its lead product candidate includes the ZN-c3, an inhibitor of WEE1, a protein tyrosine kinase, which is in Phase 2 clinical trial for the treatment of advanced solid tumors; Phase 1/2 clinical trial for the treatment of advanced solid tumors as a monotherapy and in an ongoing Phase 1b clinical trial in combination with chemotherapy in patients with platinum resistant ovarian cancer; and Phase 2 monotherapy trial for a tumor agnostic, predictive biomarker.
The company's other lead product candidate includes ZN-c5, an oral selective estrogen receptor degrader that is in a Phase 1/2 clinical trial for the treatment of advanced estrogen receptor-positive, human epidermal growth factor receptor 2-negative, or advanced or metastatic breast cancer. In addition, it is involved in developing ZN-d5, a selective inhibitor of B-cell lymphoma 2 that is in a Phase 1 clinical trial for the treatment of non-Hodgkin's lymphoma and acute myelogenous leukemia; and ZN-e4, an irreversible inhibitor of mutant epidermal growth factor receptor, which is in Phase 1/2 clinical trial for the treatment of advanced non-small cell lung cancer. Further, the company is developing BCL-xL heterobifunctional degraders based on E3 ligases not expressed in platelets, allowing for the avoidance of dose-limiting thrombocytopenia associated with BCL-xL inhibitors. Zentalis Pharmaceuticals, Inc. has licensing agreements and strategic collaborations with Recurium IP Holdings, LLC; Mayo Foundation for Medical Education and Research; SciClone Pharmaceuticals International (Cayman) Development Ltd.; Pfizer, Inc.; Eli Lilly and Company; GlaxoSmithKline, and Zentera Therapeutics (Cayman), Ltd. The company was incorporated in 2014 and is based in New York, New York.
Pin risk into expiration, dealer positioning, liquidity checks for large orders — all of it starts with knowing where ZNTL open interest is concentrated. Our scanner maps Zentalis Pharmaceuticals Inc's open interest across every strike and expiry, flags unusual buildups, and lets you drill into the contracts that institutional money is actually holding. Trade Zentalis Pharmaceuticals Inc's options open interest as the signal it is, not as an afterthought.
| 5.00 | — | 0.85 | 0.85 | 592% | +0.5538 | 2,611 |
| 2.50 | — | 2.85 | 2.85 | 1,000% | +0.8616 | 92 |
| 0.50 | 0.05 | 4.60 | 2.33 | 615% | +0.9762 | 69 |
| 7.50 | — | 1.30 | 1.30 | 908% | +0.6607 | 16 |
| 1.00 | 0.05 | 4.10 | 2.08 | 708% | +0.9235 | 0 |
| 1.50 | — | 2.45 | 2.45 | 1,000% | -0.0911 | 52 |
| 2.50 | — | 0.30 | 0.30 | 196% | -0.3228 | 32 |
| 5.00 | 1.45 | 4.60 | 3.03 | 572% | -0.4613 | 32 |
| 7.50 | 2.60 | 7.10 | 4.85 | 357% | -0.8350 | 9 |
| 0.50 | — | 0.05 | 0.05 | 602% | -0.0229 | 0 |
As of October 1, 2026
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