Denali Therapeutics Inc

DNLINASDAQ · USD
18.68USD0.00 (-1.33%)
127

Denali Therapeutics Inc (DNLI) Straddle

DNLI straddle scan found 13 qualifying long straddle setups on the previous trading day. Probability of profit reaches up to 54.7%.

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Trading a DNLI straddle lets you take a pure volatility position on Denali Therapeutics Inc without committing to a direction. Denali Therapeutics Inc's straddle involves buying (or selling) a call and a put at the same strike and expiration, profiting when the stock moves more (or less) than the combined premium implies. Use our scanner to evaluate DNLI straddle pricing in real time and find the moments when expected moves are mispriced.

A long straddle on DNLI profits from large moves in either direction and is a classic play into binary events like earnings, product announcements, or macro releases. A short straddle profits when Denali Therapeutics Inc stays range-bound and implied volatility contracts. The breakeven points are simple: strike plus total premium on the upside, strike minus total premium on the downside. Comparing the DNLI straddle price to historical realized moves helps you judge whether the market is overpaying or underpaying for volatility.

Denali Therapeutics Inc., a biopharmaceutical company, discovers and develops therapeutic candidates for neurodegenerative diseases in the United States. It offers leucine-rich repeat kinase 2 (LRRK2) inhibitor product candidate, including BIIB122/DNL151, a small molecule inhibitor, which is in phase I and phase Ib clinical trials for the treatment of Parkinson's disease. The company also develops DNL310 that is in Phase I/II clinical trials for the treatment of hunter syndrome; DNL343, which is in phase 1 clinical trial the treatment of amyotrophic lateral sclerosis (ALS); AR443820/DNL788 completed a phase I clinical trial for the treatment of ALS, multiple sclerosis (MS), and Alzheimer's disease; and SAR443122/DNL758, which is in phase II clinical trial for the treatment of cutaneous lupus erythematosus.

It has collaboration agreement with Takeda Pharmaceutical Company, Genentech, Inc., Sanofi, F-star Gamma Limited, F-star Biotechnologische Forschungs-Und Entwicklungsges M.B.H, F-star Biotechnology Limited, SIRION Biotech GmbH, Genzyme Corporation, Harvard University, the Michael J. Fox Foundation, and Centogene; and a research and option agreement with Secarna Pharmaceuticals GmbH & Co. KG. to develop antisense therapies in the field of neurodegenerative diseases. The company was formerly known as SPR Pharma Inc. and changed its name to Denali Therapeutics Inc. in March 2015. Denali Therapeutics Inc. was incorporated in 2013 and is headquartered in South San Francisco, California.

Earnings, product cycles, macro prints — any time volatility itself is the trade, the DNLI straddle is the cleanest expression of that view. Our scanner prices every DNLI straddle against historical realized moves, flags expirations where the market is overpaying or underpaying for vol, and ranks setups by breakeven width and IV rank. Whether you're long a DNLI straddle into a catalyst or short a DNLI straddle to harvest decay, the options straddle setups that matter are all in one place.

Jun 17, 202725.00$10.7524068%54.7%$35.75$14.250
Mar 19, 202725.00$9.1315068%54.2%$34.13$15.8899
Mar 19, 202722.50$7.9315068%51.8%$30.43$14.58610
Jun 17, 202722.50$9.7824068%51.2%$32.28$12.730
Dec 18, 202625.00$7.405968%50.4%$32.40$17.60116
Mar 19, 202735.00$18.4015068%50.3%$53.40$16.6030
Mar 19, 202720.00$6.8815068%50.0%$26.88$13.1376
Nov 20, 202622.50$4.803168%47.7%$27.30$17.706
Jun 17, 202720.00$9.1824068%45.9%$29.18$10.830
Mar 19, 202717.50$6.6315068%44.5%$24.13$10.8840

As of October 21, 2026

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Track DNLI straddle pricing across expirations, filter by IV rank and breakeven points, and build a setup that fits your view before the move happens.

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