Denali Therapeutics Inc

DNLINASDAQ · USD
20.81USD-0.17 (-0.81%)
139

Denali Therapeutics Inc (DNLI) Unusual Options Activity Today

DNLI options volume power reached 1.94x on the previous trading day. The highest reading was on the $25 CALL expiring 2027-03-19.

Read more

Checking DNLI unusual options activity helps you spot when traders are making outsized bets on Denali Therapeutics Inc before the broader market catches on. Denali Therapeutics Inc's unusual options activity flags contracts trading at multiples of their average daily volume, often signaling that informed money is positioning ahead of a catalyst. Use our scanner to monitor DNLI unusual options activity today and surface the prints that deserve a second look.

Unusual options flow typically refers to trades where volume vastly exceeds open interest at a given strike, or where total contract volume on a name spikes well above its norm. Watching DNLI unusual options flow today can reveal large block trades, sweeps across exchanges, and aggressive directional bets. Tracking DNLI unusual options volume across calls and puts helps you separate hedging activity from genuinely speculative positioning, and DNLI unusual options flow data becomes especially valuable around earnings, product launches, and macro events.

Denali Therapeutics Inc., a biopharmaceutical company, discovers and develops therapeutic candidates for neurodegenerative diseases in the United States. It offers leucine-rich repeat kinase 2 (LRRK2) inhibitor product candidate, including BIIB122/DNL151, a small molecule inhibitor, which is in phase I and phase Ib clinical trials for the treatment of Parkinson's disease. The company also develops DNL310 that is in Phase I/II clinical trials for the treatment of hunter syndrome; DNL343, which is in phase 1 clinical trial the treatment of amyotrophic lateral sclerosis (ALS); AR443820/DNL788 completed a phase I clinical trial for the treatment of ALS, multiple sclerosis (MS), and Alzheimer's disease; and SAR443122/DNL758, which is in phase II clinical trial for the treatment of cutaneous lupus erythematosus.

It has collaboration agreement with Takeda Pharmaceutical Company, Genentech, Inc., Sanofi, F-star Gamma Limited, F-star Biotechnologische Forschungs-Und Entwicklungsges M.B.H, F-star Biotechnology Limited, SIRION Biotech GmbH, Genzyme Corporation, Harvard University, the Michael J. Fox Foundation, and Centogene; and a research and option agreement with Secarna Pharmaceuticals GmbH & Co. KG. to develop antisense therapies in the field of neurodegenerative diseases. The company was formerly known as SPR Pharma Inc. and changed its name to Denali Therapeutics Inc. in March 2015. Denali Therapeutics Inc. was incorporated in 2013 and is headquartered in South San Francisco, California.

Catalysts rarely arrive without a footprint, and DNLI unusual options activity is often where that footprint shows up first. Our scanner tracks Denali Therapeutics Inc's unusual options flow in real time, ranks prints by volume-to-open-interest, premium spent, and aggressor side, and separates real conviction from noise. Whether you're looking at DNLI unusual options volume on the call side or chasing put sweeps, Denali Therapeutics Inc's unusual options flow today is one click away, so put it on your radar before the headlines hit.

2026-10-16
Calls
22.50—2.802.80185%1185.56%
20.00—1.501.5066%11680.60%
12.505.9010.108.00121%00—
15.003.407.605.5081%00—
17.501.505.103.3076%00—
Puts
12.50—2.152.15348%00—
15.00—2.152.15264%010.00%
17.50—1.001.00121%030.00%
20.00—1.501.5089%10—
22.500.704.302.5059%50—

As of September 28, 2026

Spot unusual options activity before it moves

Track DNLI options flow across every expiration, filter by volume power, and find the setups with abnormal activity before the trade is gone.

Start your 14-day free trial