Ionis Pharmaceuticals Inc
Ionis Pharmaceuticals Inc (IONS) Wheel Strategy
IONS wheel strategy scan found 41 cash-secured put setups on the previous trading day. Probability of expiring worthless is above 50%. Annualized returns reach up to 46.0%.
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Running a IONS wheel strategy lets you generate consistent premium income on Ionis Pharmaceuticals Inc while setting your own entry and exit prices on the underlying. Ionis Pharmaceuticals Inc's wheel combines cash-secured puts and covered calls into a repeatable cycle: sell puts at strikes where you'd be happy to own IONS, and if assigned, sell calls at strikes where you'd be happy to sell. Use our scanner to find the best IONS wheel strategy setups in real time.
The wheel works best on liquid, high-quality names with stable fundamentals and active options markets — exactly the profile many large-cap leaders fit. The mechanics are simple: sell a cash-secured put on IONS, collect premium, and either keep the premium if it expires worthless or take assignment at a discount to current price. Once assigned, sell covered calls against the shares to keep collecting premium until they're called away. Choosing the right strikes, expirations, and IV environment is what separates a profitable IONS wheel from a losing one.
Ionis Pharmaceuticals, Inc. discovers and develops RNA-targeted therapeutics in the United States. The company offers SPINRAZA for spinal muscular atrophy (SMA) in pediatric and adult patients; TEGSEDI, an injection for the treatment of polyneuropathy of hereditary transthyretin-mediated amyloidosis in adults; and WAYLIVRA, a treatment for familial chylomicronemia syndrome and familial partial lipodystrophy. It also develops medicines for various indications that are in phase 3 study, including Eplontersen as a monthly self-administered subcutaneous injection to treat all types of TTR amyloidosis; Olezarsen for patients with severe hypertriglyceridemia (SHTG); Donidalorsen for patients with hereditary angioedema; ION363 for patients with amyotrophic lateral sclerosis; Pelacarsen for patients with established cardiovascular disease and elevated lipoprotein(a); and Tofersen to inhibit the production of superoxide dismutase 1.
In addition, the company develops medicines for metabolic diseases, infectious diseases, renal diseases, ophthalmic diseases, and cancer. It has a strategic collaboration with Biogen Inc.; and collaboration and license agreement with AstraZeneca, Bayer AG, GlaxoSmithKline plc, Novartis AG, Roche, Janssen Biotech, Inc., and Flamingo Therapeutics, Inc. Ionis Pharmaceuticals, Inc. was founded in 1989 and is based in Carlsbad, California.
The difference between a wheel that compounds and one that bleeds comes down to strike selection, IV timing, and discipline on assignment. Our scanner handles the heavy lifting: it ranks every leg of the IONS wheel strategy by delta, premium yield, IV rank, and days to expiration, so you can deploy capital where the math works. Build your IONS wheel strategy on data, not gut feel — and let the options wheel do what it does best: pay you to wait.
| Oct 16, 2026 | 42.50 | $1.20 | $1.50 | -0.34 | 28 | 43% | 62.5% | 46.0% | 513 |
| Nov 20, 2026 | 42.50 | $1.65 | $2.63 | -0.36 | 63 | 43% | 57.0% | 35.8% | 8 |
| Dec 18, 2026 | 42.50 | $3.10 | $3.45 | -0.37 | 91 | 43% | 55.0% | 32.6% | 48 |
| Nov 20, 2026 | 40.00 | $1.70 | $2.18 | -0.28 | 63 | 43% | 69.0% | 31.5% | 2 |
| Jan 15, 2027 | 42.50 | $3.00 | $3.95 | -0.37 | 119 | 43% | 53.6% | 28.5% | 34 |
| Jan 15, 2027 | 40.00 | $1.85 | $3.03 | -0.30 | 119 | 43% | 62.6% | 23.2% | 147 |
| Oct 16, 2026 | 40.00 | $0.65 | $0.70 | -0.19 | 28 | 43% | 78.9% | 22.8% | 3,086 |
| Dec 18, 2026 | 40.00 | $1.65 | $2.25 | -0.28 | 91 | 43% | 65.2% | 22.6% | 11 |
| Dec 18, 2026 | 37.50 | $1.55 | $2.05 | -0.23 | 91 | 43% | 75.0% | 21.9% | 10 |
| Nov 20, 2026 | 37.50 | $0.65 | $1.38 | -0.20 | 63 | 43% | 79.9% | 21.2% | 1 |
As of September 18, 2026
Run the Wheel on IONS With Confidence
Find the best IONS wheel strategy setups across strikes and expirations, plan ahead with at-strike values, and keep your covered calls and puts on track.
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