Septerna Inc

SEPNNASDAQ · USD
37.73USD-2.65 (-6.57%)
3310

Septerna Inc (SEPN) Options Open Interest

SEPN options open interest is 2,592 contracts. The 2-week average daily volume is 33 contracts across the chain.

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Monitoring SEPN open interest helps you see where real money is positioned on Septerna Inc's options and which strikes are attracting the most commitment from traders. Septerna Inc's open interest reflects the total number of outstanding contracts that have not been closed or exercised, making it a powerful gauge of liquidity, conviction, and potential support and resistance zones. Use our scanner to monitor SEPN options open interest in real time and find the strikes that matter.

Open interest is distinct from volume: volume counts how many contracts are traded in a session, while open interest counts how many remain open at the end of the day. Rising SEPN options open interest alongside rising volume suggests new positions are being built, while falling open interest signals positions are being closed. Heavy open interest at specific strikes often acts as a magnet near expiration and can hint at where dealers and large traders expect Septerna Inc to settle.

Septerna, Inc., a clinical-stage biotechnology company, discovers and develops G protein-coupled receptor (GPCR) oral small molecule products candidates for the treatment of endocrinology, immunology and inflammation, and metabolic diseases. The company develops SEP-786, an oral small molecule PTH1R agonist for hypoparathyroidism; SEP-631, an oral small molecule MRGPRX2 NAM for chronic spontaneous urticaria and other mast cell diseases; TSHR Program, an oral small molecule TSHR NAM for Graves' disease and thyroid eye disease. It also develops oral small molecule single- and multi-incretin receptor agonists for metabolic disorders including obesity and type 2 diabetes.

Septerna, Inc. was formerly known as GPCR NewCo, Inc. and changed its name to Septerna Inc. in June 2021. The company was incorporated in 2019 and is headquartered in South San Francisco, California.

Pin risk into expiration, dealer positioning, liquidity checks for large orders — all of it starts with knowing where SEPN open interest is concentrated. Our scanner maps Septerna Inc's open interest across every strike and expiry, flags unusual buildups, and lets you drill into the contracts that institutional money is actually holding. Trade Septerna Inc's options open interest as the signal it is, not as an afterthought.

2026-10-16
Calls
33.006.0010.408.2085%+0.853050
39.001.505.403.4566%+0.620540
42.000.904.802.8585%+0.475819
50.004.304.30181%+0.409713
30.009.0013.0011.00101%+0.901411
Puts
42.002.305.503.9074%-0.540210
43.003.006.004.5073%-0.591410
38.001.154.903.03105%-0.35535
40.001.104.903.0079%-0.43625
25.001.901.90221%-0.12774

As of September 22, 2026

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Track SEPN open interest across every strike and expiration, identify where conviction is building, and trade with the positioning data on your side.

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