Septerna Inc
Septerna Inc (SEPN) Unusual Options Activity Today
SEPN options volume power reached 0x on the previous trading day. The highest reading was on the $21 CALL expiring 2026-10-16.
Read more
Checking SEPN unusual options activity helps you spot when traders are making outsized bets on Septerna Inc before the broader market catches on. Septerna Inc's unusual options activity flags contracts trading at multiples of their average daily volume, often signaling that informed money is positioning ahead of a catalyst. Use our scanner to monitor SEPN unusual options activity today and surface the prints that deserve a second look.
Unusual options flow typically refers to trades where volume vastly exceeds open interest at a given strike, or where total contract volume on a name spikes well above its norm. Watching SEPN unusual options flow today can reveal large block trades, sweeps across exchanges, and aggressive directional bets. Tracking SEPN unusual options volume across calls and puts helps you separate hedging activity from genuinely speculative positioning, and SEPN unusual options flow data becomes especially valuable around earnings, product launches, and macro events.
Septerna, Inc., a clinical-stage biotechnology company, discovers and develops G protein-coupled receptor (GPCR) oral small molecule products candidates for the treatment of endocrinology, immunology and inflammation, and metabolic diseases. The company develops SEP-786, an oral small molecule PTH1R agonist for hypoparathyroidism; SEP-631, an oral small molecule MRGPRX2 NAM for chronic spontaneous urticaria and other mast cell diseases; TSHR Program, an oral small molecule TSHR NAM for Graves' disease and thyroid eye disease. It also develops oral small molecule single- and multi-incretin receptor agonists for metabolic disorders including obesity and type 2 diabetes.
Septerna, Inc. was formerly known as GPCR NewCo, Inc. and changed its name to Septerna Inc. in June 2021. The company was incorporated in 2019 and is headquartered in South San Francisco, California.
Catalysts rarely arrive without a footprint, and SEPN unusual options activity is often where that footprint shows up first. Our scanner tracks Septerna Inc's unusual options flow in real time, ranks prints by volume-to-open-interest, premium spent, and aggressor side, and separates real conviction from noise. Whether you're looking at SEPN unusual options volume on the call side or chasing put sweeps, Septerna Inc's unusual options flow today is one click away, so put it on your radar before the headlines hit.
| 15.00 | 20.60 | 25.50 | 23.05 | 232% | 0 | 0 | — |
| 16.00 | 19.60 | 24.50 | 22.05 | 217% | 0 | 0 | — |
| 17.00 | 18.70 | 23.50 | 21.10 | 211% | 0 | 0 | — |
| 18.00 | 17.60 | 22.50 | 20.05 | 189% | 0 | 0 | — |
| 19.00 | 16.50 | 21.30 | 18.90 | 147% | 0 | 0 | — |
| 15.00 | — | 3.80 | 3.80 | 543% | 0 | 0 | — |
| 16.00 | — | 3.80 | 3.80 | 511% | 0 | 0 | — |
| 17.00 | — | 3.80 | 3.80 | 482% | 0 | 0 | — |
| 18.00 | — | 3.80 | 3.80 | 455% | 0 | 0 | — |
| 19.00 | — | 3.80 | 3.80 | 430% | 0 | 0 | — |
As of September 28, 2026
Spot unusual options activity before it moves
Track SEPN options flow across every expiration, filter by volume power, and find the setups with abnormal activity before the trade is gone.
Start your 14-day free trial→