Spyre Therapeutics Inc

SYRENASDAQ · USD
89.03USD0.00 (+5.09%)
1210

Spyre Therapeutics Inc (SYRE) Covered Calls

As of September 30, 2026, SYRE has 64 covered call opportunities in the coming three months. Return ranges from 3.0 to 98.9% until expiration. Annualized return ranges from 24.5 to 298.2%. The nearest expiration is October 16, 2026. Maximum potential profit is $8,378.

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Running SYRE covered calls helps you generate consistent income from Spyre Therapeutics Inc's shares you already own, turning a long stock position into a yield-producing asset. A covered call on Spyre Therapeutics Inc involves holding the underlying stock and selling a call option against it, collecting premium in exchange for capping upside at the strike price. Use our scanner to find the best SYRE covered calls in real time and filter for the strikes, expiries, and premiums that fit your strategy.

A covered call is one of the most widely used options strategies because it pairs limited risk with a clear income profile: if SYRE stays below the strike at expiration, you keep the premium and the shares; if it rises above, you deliver the stock at the strike and still pocket the premium. Selling SYRE covered calls works best when implied volatility is elevated, since richer premiums improve the risk-reward. Key inputs to evaluate include strike selection relative to delta, days to expiration, annualized return, and the probability of assignment — all of which determine whether a given Spyre Therapeutics Inc covered call is worth writing.

Spyre Therapeutics, Inc., a preclinical stage biotechnology company, focuses on developing therapeutics for patients living with inflammatory bowel disease (IBD). It develops SPY001, a human monoclonal immunoglobulin G1 antibody designed to bind selectively to the a4ß7 integrin being developed for the treatment of IBD (ulcerative colitis and Crohn's disease). The company is also developing SPY002, a human monoclonal antibody (mAb)candidates designed to bind to tumor necrosis factor-like ligand 1A; and SPY120, a combination of SPY001 (anti-a4ß7) and SPY002 (anti-TL1A) antibodies, which are in preclinical studies.

In addition, its other early-stage programs include SPY003, an anti-IL-23 mAb; SPY004, a novel mechanism of action (MOA) mAb; SPY130, a combination of anti-a4ß7 and anti-IL-23 mAbs; and SPY230, a combination of anti-TL1A and anti-IL-23 mAbs. The company was formerly known as Aeglea BioTherapeutics, Inc. and changed its name to Spyre Therapeutics, Inc. in November 2023. Spyre Therapeutics, Inc. was incorporated in 2013 and is based in Waltham, Massachusetts.

Income-focused investors, long-term SYRE holders, and systematic premium sellers all face the same challenge: finding the covered call strike and expiry that balances yield against the risk of being called away. Our scanner ranks covered calls by annualized return, downside protection, and probability of profit, so selling SYRE covered calls becomes a measured decision instead of a guess. Stop eyeballing the chain — let the best Spyre Therapeutics Inc covered calls come to you, already filtered for the metrics that matter.

Stock Statistics

  • IndustryBiotechnology
  • SectorHealthcare
  • IV percentile37.30% Neutral
  • Market cap (M$)7,850
  • 52 weeks high-19.20%
  • 52 weeks low461.35%
  • Analyst recommendationStrong Buy
    1.21
  • Target price$121.67
    36.66% above the current stock price
  • Dividend—
  • Payout ratio—
  • Earnings date2026-11-03
  • P/E—
  • Future P/E—
  • EPS (ttm)-2.18
  • EPS growth next 5 years-28.76%

As of September 30, 2026

2026-12-1880140.0065.250.105.005538.0065.37298.24-0.12+0.1604.90
2026-11-2052120.0041.640.105.003538.0041.76293.13-0.12+0.1984.90
2026-10-161795.0012.130.504.901078.0012.72273.20-0.59+0.30144.40
2026-12-1880135.0059.350.105.005038.0059.47271.32-0.12+0.1704.90
2026-11-2052115.0035.740.105.003038.0035.86251.70-0.12+0.2094.90
2026-12-1880125.0047.540.105.004038.0047.66217.46-0.12+0.1804.90
2026-11-2052110.0029.840.105.002538.0029.96210.28-0.12+0.2234.90
2027-01-15108135.0059.350.105.005038.0059.47200.97-0.12+0.1704.90
2026-12-1880120.0041.640.105.003538.0041.76190.53-0.12+0.1904.90
2027-03-19171160.0088.860.105.007538.0088.98189.92-0.12+0.1504.90

As of September 30, 2026

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