Spyre Therapeutics Inc
Spyre Therapeutics Inc (SYRE) Straddle
SYRE straddle scan found 100 qualifying long straddle setups on the previous trading day. Probability of profit reaches up to 53.4%.
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Trading a SYRE straddle lets you take a pure volatility position on Spyre Therapeutics Inc without committing to a direction. Spyre Therapeutics Inc's straddle involves buying (or selling) a call and a put at the same strike and expiration, profiting when the stock moves more (or less) than the combined premium implies. Use our scanner to evaluate SYRE straddle pricing in real time and find the moments when expected moves are mispriced.
A long straddle on SYRE profits from large moves in either direction and is a classic play into binary events like earnings, product announcements, or macro releases. A short straddle profits when Spyre Therapeutics Inc stays range-bound and implied volatility contracts. The breakeven points are simple: strike plus total premium on the upside, strike minus total premium on the downside. Comparing the SYRE straddle price to historical realized moves helps you judge whether the market is overpaying or underpaying for volatility.
Spyre Therapeutics, Inc., a preclinical stage biotechnology company, focuses on developing therapeutics for patients living with inflammatory bowel disease (IBD). It develops SPY001, a human monoclonal immunoglobulin G1 antibody designed to bind selectively to the a4ß7 integrin being developed for the treatment of IBD (ulcerative colitis and Crohn's disease). The company is also developing SPY002, a human monoclonal antibody (mAb)candidates designed to bind to tumor necrosis factor-like ligand 1A; and SPY120, a combination of SPY001 (anti-a4ß7) and SPY002 (anti-TL1A) antibodies, which are in preclinical studies.
In addition, its other early-stage programs include SPY003, an anti-IL-23 mAb; SPY004, a novel mechanism of action (MOA) mAb; SPY130, a combination of anti-a4ß7 and anti-IL-23 mAbs; and SPY230, a combination of anti-TL1A and anti-IL-23 mAbs. The company was formerly known as Aeglea BioTherapeutics, Inc. and changed its name to Spyre Therapeutics, Inc. in November 2023. Spyre Therapeutics, Inc. was incorporated in 2013 and is based in Waltham, Massachusetts.
Earnings, product cycles, macro prints — any time volatility itself is the trade, the SYRE straddle is the cleanest expression of that view. Our scanner prices every SYRE straddle against historical realized moves, flags expirations where the market is overpaying or underpaying for vol, and ranks setups by breakeven width and IV rank. Whether you're long a SYRE straddle into a catalyst or short a SYRE straddle to harvest decay, the options straddle setups that matter are all in one place.
| Mar 19, 2027 | 160.00 | $75.40 | 177 | 2% | 53.4% | $235.40 | $84.60 | 0 |
| Mar 19, 2027 | 155.00 | $70.93 | 177 | 2% | 53.1% | $225.93 | $84.08 | 0 |
| Mar 19, 2027 | 150.00 | $66.80 | 177 | 2% | 52.3% | $216.80 | $83.20 | 0 |
| Jan 15, 2027 | 155.00 | $69.55 | 114 | 2% | 51.9% | $224.55 | $85.45 | 0 |
| Jan 15, 2027 | 160.00 | $74.65 | 114 | 2% | 51.7% | $234.65 | $85.35 | 0 |
| Jan 15, 2027 | 145.00 | $60.00 | 114 | 2% | 51.5% | $205.00 | $85.00 | 0 |
| Jan 15, 2027 | 150.00 | $64.90 | 114 | 2% | 51.5% | $214.90 | $85.10 | 0 |
| Jan 15, 2027 | 140.00 | $55.20 | 114 | 2% | 51.5% | $195.20 | $84.80 | 0 |
| Mar 19, 2027 | 145.00 | $63.15 | 177 | 2% | 51.1% | $208.15 | $81.85 | 0 |
| Jan 15, 2027 | 135.00 | $50.78 | 114 | 2% | 51.0% | $185.78 | $84.23 | 0 |
As of September 25, 2026
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Track SYRE straddle pricing across expirations, filter by IV rank and breakeven points, and build a setup that fits your view before the move happens.
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