Spyre Therapeutics Inc
Spyre Therapeutics Inc (SYRE) Option Chain
As of October 26, 2026, Spyre Therapeutics Inc is trading at $99.04, a +6.61% change from the previous close. The nearest expiration is Nov 20, 2026. Implied volatility is 73.2%. IV Rank is 16%.
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Tracking the SYRE option chain helps you see every strike and expiry on Spyre Therapeutics Inc in one view, so you can quickly identify the contracts that fit your thesis and your risk. Spyre Therapeutics Inc's option chain lays out bids, asks, volume, open interest, and Greeks across calls and puts, giving you the full map of SYRE options activity at a glance. Use our scanner to monitor the SYRE option chain in real time and filter for the SYRE options trades that actually meet your criteria.
An option chain is the complete listing of all available option contracts on an underlying, organized by expiration date and strike price. For SYRE stock options, the chain shows side-by-side call and put data, making it easy to compare premiums, assess liquidity, and spot pricing dislocations. Reading the SYRE option chain effectively means looking beyond the last price — implied volatility by strike, volume-to-open-interest ratios, and bid-ask spreads all tell you where SYRE stock options are being actively traded and where they are not.
Spyre Therapeutics, Inc., a preclinical stage biotechnology company, focuses on developing therapeutics for patients living with inflammatory bowel disease (IBD). It develops SPY001, a human monoclonal immunoglobulin G1 antibody designed to bind selectively to the a4ß7 integrin being developed for the treatment of IBD (ulcerative colitis and Crohn's disease). The company is also developing SPY002, a human monoclonal antibody (mAb)candidates designed to bind to tumor necrosis factor-like ligand 1A; and SPY120, a combination of SPY001 (anti-a4ß7) and SPY002 (anti-TL1A) antibodies, which are in preclinical studies.
In addition, its other early-stage programs include SPY003, an anti-IL-23 mAb; SPY004, a novel mechanism of action (MOA) mAb; SPY130, a combination of anti-a4ß7 and anti-IL-23 mAbs; and SPY230, a combination of anti-TL1A and anti-IL-23 mAbs. The company was formerly known as Aeglea BioTherapeutics, Inc. and changed its name to Spyre Therapeutics, Inc. in November 2023. Spyre Therapeutics, Inc. was incorporated in 2013 and is based in Waltham, Massachusetts.
Credit spreads, long calls, iron condors, calendar trades — every strategy starts with the same raw material: a clean, complete option chain. Our scanner pulls Spyre Therapeutics Inc's full chain across every expiry, highlights the most liquid strikes, and lets you screen SYRE options by the metrics that matter, from IV skew to volume surges. Stop scrolling through endless rows of SYRE stock options — let the full option chain come to you, pre-filtered and ready to trade.
Stock Statistics
- IndustryBiotechnology
- SectorHealthcare
- IV percentile21.03% Subdued
- Market cap (M$)9,141
- 52 weeks high-10.11%
- 52 weeks low368.50%
- Analyst recommendationStrong Buy
1.18 - Target price$122.33
23.52% above the current stock price - Dividend—
- Payout ratio—
- Earnings date2026-11-03
- P/E—
- Future P/E—
- EPS (ttm)-2.18
- EPS growth next 5 years-27.79%
As of October 26, 2026
| CALLs | PUTs | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Prob. OTM % | Open Interest | Volume | Extrinsic Value | Intrinsic Value | Bid | Ask | Strike | Moneyness % | Bid | Ask | Intrinsic Value | Extrinsic Value | Volume | Open Interest | Prob. OTM % |
| 46.99 | 15 | 0 | -0.14 | 9.04 | 7.00 | 10.80 | 90.00 | -3.13 | 4.00 | 8.20 | 0.00 | 6.10 | 0 | 3 | 53.01 |
| 57.83 | 35 | 0 | 2.41 | 4.04 | 4.50 | 8.40 | 95.00 | +2.25 | 6.50 | 10.50 | 0.00 | 8.50 | 0 | 7 | 42.17 |
| 67.61 | 3 | 0 | 4.65 | 0.00 | 2.80 | 6.50 | 100.00 | +7.63 | 9.50 | 13.50 | 0.96 | 10.54 | 0 | 2 | 32.39 |
| 75.90 | 2 | 0 | 3.35 | 0.00 | 1.50 | 5.20 | 105.00 | +13.01 | 13.00 | 17.30 | 5.96 | 9.19 | 0 | 0 | 24.10 |
| 82.59 | 9 | 0 | 2.50 | 0.00 | 0.10 | 4.90 | 110.00 | +18.39 | 17.00 | 21.30 | 10.96 | 8.19 | 0 | 4 | 17.41 |
As of October 26, 2026
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